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¹Çankırı Devlet Hastanesi, Beyin ve Sinir Cerrahisi Kliniği, Çankırı, Türkiye
²Tuzla Devlet Hastanesi, Beyin ve Sinir Cerrahisi Kliniği, İstanbul, Türkiye Also known as brain-computer interfaces, brain-machine interfaces (BMI) are applications that create a direct link between the brain or specific neurons and a computer, in order to usually control a prosthesis. There have been exciting developments in the last decade in the use of BMI for clinical disorders. Restoring communication in speech disorders after amyotrophic lateral sclerosis or stroke, restoring mobilization after motor neuron disease or spinal trauma, and restoring memory after cognitive dysfunction are some of the areas of BMI. Since BMI is controlled by specific neurons or a specific cortical area, it has also allowed us to better understand brain physiology and learning. This review will focus on the use of BMI in clinical and research applications with emphasis on motor BMI. Anahtar Kelimeler : Brain-computer interfaces, Brain-machine interfaces, Motor cortex, Neuroprosthesis, Neurorehabilitation, Paralysis