Türk Nöroşirürji Dergisi 2015 , Vol 25 , Num 3
A Clinical Problem that should not be Forgotten in Head Trauma: Post-Traumatic Epilepsy
Samiye USLU KUZUDİŞLİ1, Sırma GEYİK2, Abidin Murat GEYİK3, Mehmet DOKUR4
1Zirve Üniversitesi, EBN Tıp Fakültesi, Nöroloji Anabilim Dalı, Gaziantep, Türkiye
2Gaziantep Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Gaziantep, Türkiye
3Gaziantep Üniversitesi, Tıp Fakültesi, Nöroşirürji Anabilim Dalı, Gaziantep, Türkiye
4Zirve Üniversitesi, EBN Tıp Fakültesi, Acil Tıp Anabilim Dalı, Gaziantep, Türkiye
Traumatic brain injury may lead to secondary posttraumatic epilepsy. The condition mainly aff ects young male adults and has an important place in the etiology of new-onset generalized epilepsy. Post-traumatic epilepsy plays an important role in the etiology of new-onset generalized tonic-clonic epilepsy and various gene polymorphisms are accused in the etiology. The pathogenesis, prognosis and management of early and late seizures occurring after traumatic brain injury are diff erent from each other. The risk of relapse is higher in late posttraumatic epilepsy. Electroencephalography and magnetic resonance imaging are important in patients with post-traumatic epilepsy for the diagnosis and clinical monitoring. In recent years, the new antiepileptic drug levetiracetam has come to the fore in the treatment of posttraumatic epilepsy. As non-drug treatments, vagal nerve stimulation and electrical stimulation of the brain and surgical treatment of the epileptogenic focus may be considered in treatment-resistant patients and in late cases. This review article aims to provide information on the pathogenesis and approach to the treatment of post-traumatic epilepsy patients in the light of the current literature. Anahtar Kelimeler : Head trauma, Post-traumatic epilepsy, Current treatment