Türk Nöroşirürji Dergisi 2011 , Vol 21 , Num 3
Eosinophilic Granuloma: Radiological and Clinical Evaluation
Mehmet BASMACI, Aşkın Esen HASTÜRK
S.B. Onkoloji Eğitim ve Araştırma Hastanesi, Nöroşirürji Bölümü, Ankara, Türkiye 90% of cases of eosinophilic granuloma (EG) occur in children under ten years of age. It is a rare, benign bone tumor, involving the head and vertebral bones, with a controversial etiology. EG is characterized by either single or multiple lytic-bone lesions. It develops by the accumulation of eosinophils and histiocytes on the medullary layer of the bone. The diagnosis is confirmed pre-operatively with X-rays, bone scintigraphy, CT, MRI and histological examination after surgery. Eosinophilic granuloma does not lead to malignant transformation. Eosinophilic granuloma can be followed up without treatment if there are no symptoms. The treatment of painful lesion can be with surgical curettage of the tumor or local infusion of cortisone. Chemotherapy, radiotherapy and systemic use of cortisone are effective for multiple bone lesions. In this case report, we present a four-year-old male patient admitted to our clinic with complaints of swelling in the right parietal region and local pain. Anahtar Kelimeler : Eosinophilic granuloma, Bone tumor, Skull, Treatment