Türk Nöroşirürji Dergisi
1992 , Vol 2 , Num 4
DETERMINATION OF GLIAL FIBRILLARY ACIDIC PROTEIN AND NEUROFILAMENTS IN BRAIN TUMORS
1Ege Üniversitesi Tıp Fakültesi, Tıbbi Biyoloji Anabilim Dalı, İzmir2Dokuz Eylül Üniversitesi, Tıp Fakültesi, Tıbbi Biyoloji Anabilim Dalı, İzmir
3Ege Üniversitesi Tıp Fakültesi, Nöroşirürji Anabilim Dalı, İzmir
4Ege Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, İzmir In this study, tbe classification of tumors, determination of the relationship between a tumor and a ''grade'' on the cell culture, prepared from the various human brain tumors are planned and using these findings about intermediate filaments to assist the pathological diagnosis is aimed.
In conclusion, GFAP and NF nonspecific fluorescence staining was not seen on control group. Negative fluorescence staining was observed in various neoplasms (neurinoma, non-Hodgin lenfoma, papillary adenocarcinoma) which were not glial tumors. Positive fluorescence staining was observed in various type of glial tumors.
Positive reaction against NF antibody was not seen on the tumors which are being examined
Anahtar Kelimeler : In vitro, human brain tumors, Glial fibrillary acidic protein, neurofilament