MATERIAL and METHODS: This single-center retrospective study included 112 patients diagnosed with meningioma based on pathology reports after undergoing surgery for intracranial tumors from January 2021 to December 2022, with complete preoperative and postoperative record.

RESULTS: Analysis of the patients' symptoms revealed 38.4% experienced headaches, 23.2% were incidental discoveries, 19.6% had dizziness (nausea-vomiting), 11.6% had seizures, and 7.1% had neurological deficits initially. Post-surgery, 9.8% underwent Gamma Knife Radiosurgery, and 15.2% received radiation therapy. Meningiomas were primarily located in the convexity (18.8%), sphenoid wing (17.8%), and olfactory groove/frontobasal area (17.8%). Histopathologically, 25.9% were meningothelial, and 23.2% were atypical subtypes. Grade 1 pathology was observed in 74.1% of the cases, and Simpson grade 2 in 51.8%. A statistically significant relationship was found between the histopathological subtype and gender, location, postoperative Gamma Knife Radiosurgery treatment, and postoperative radiation therapy treatment. Additionally, a significant statistical relationship was observed between tumor location and postoperative Gamma Knife Radiosurgery treatment status with Simpson resection grade, and between pathological grade and postoperative Gamma Knife Radiosurgery and radiation therapy treatment status.

CONCLUSION: This study presents a single-center retrospective analysis on the clinical diagnosis and treatment management of meningiomas. The significant statistical relationship between tumor location and Simpson resection grade highlights the importance of tumor location in planning surgical approaches. The importance of a multidisciplinary approach in the management of meningioma treatment is evident. Anahtar Kelimeler : Diagnosis, Gamma knife radiosurgery, Meningioma, Radiotherapy, Surgery, Treatment