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Ankara Üniversitesi, Tıp Fakültesi, Nöroşirürji Anabilim Dalı, Ankara, Türkiye Extracorporeal membrane oxygenation (ECMO) is a mechanical circulatory support used to provide pulmonary, cardiac or cardiopulmonary support for newborns, children and adults with reversible heart or lung injury. Neurological damage causes significant mortality and morbidity in patients on ECMO support. Loss of consciousness during ECMO support was observed in a patient who underwent aortic valve replacement and right coronary artery bypass and suffered postoperative cardiac arrest. A subdural hematoma was found on cranial computed tomography (CT) and the case was presented to draw attention to the intracranial complications in and clinical management of patients receiving ECMO support. The presented case is significant because it is the first reported case of subdural hematoma after ECMO in Turkey. Anahtar Kelimeler : ECMO, Subdural hematoma, Anticoagulant