Türk Nöroşirürji Dergisi 2018 , Vol 28 , Num 1
Subarachnoid Hemorrhage: Epidemiology and Genetics
Mehmet SEÇER1
1Atakent Hastanesi, Nöroşirürji Kliniği, Yalova, Türkiye Spontaneous subarachnoid hemorrhage (SAH); usually occurs after intracranial aneurysm rupture. The most important risk factors of SAH are hypertension, smoking and excessive alcohol consumption. In epidemiologic studies, first-degree relatives of SAH patients were found to have a 3- to 7-fold higher risk compared to the general population. Environmental and genetic factors play a role in the development of SAH and aneurysms and it is therefore called a complex disease. If a genetic determinant is detected in the development of SAH and aneurysms, it will facilitate screening and early treatment. However, such screening is difficult because of the complex structure of genetic diseases and the influence of multiple gene locations, the interaction between genes and the unknown transmission characteristics. The aim of this article was to review the epidemiology and the genetics of SAH. Anahtar Kelimeler : Aneurysm, Epidemiology, Genetic, Subarachnoid hemorrhage