Türk Nöroşirürji Dergisi 2021 , Vol 31 , Num 1
Brainstem Gliomas
Selahattin BİÇER1,Yusuf TÜZÜN1
1Sağlık Bilimleri Üniversitesi, Bursa Yüksek İhtisas Eğitim ve Araştırma Hastanesi, Beyin ve Sinir Cerrahisi Kliniği, Bursa, Türkiye Brainstem gliomas define a heterogeneous group of neoplasms that arise within the brainstem consisting of the mesencephalon, pons and medulla oblongata, and at other locations between the diencephalon and the cervical spinal cord. These tumors occur predominantly in children and constitute 10-20% of pediatric central nervous system tumors. Despite the frequent appearance of the triad of cranial nerve paralysis, ataxia, and long tract signs, the development of vomiting, headaches, behavioral changes, persistent hiccups, memory loss, recurring nightmares, urinary incontinence, and other symptoms within a wide spectrum is also possible. Magnetic resonance imaging provides a great advantage for the correct diagnosis and treatment planning of brainstem gliomas. There is no standardized treatment approach and surgery, radiotherapy, chemotherapy, steroids, targeted therapy, immunotherapy, and various other treatment modalities are considered depending on the patient as these lesions constitute a heterogeneous group of neoplasms and are located among eloquent brainstem structures. Anahtar Kelimeler : Brainstem tumors, Magnetic resonance imaging, Therapy