Türk Nöroşirürji Dergisi 2023 , Vol 33 , Num 3
Uncinate Fasciculus Anatomy, Functions, and Diseases
1Sağlık Bililmleri Üniversitesi, Hamidiye Tıp Fakültesi, Başakşehir Çam ve Sakura Şehir Hastanesi, Beyin ve Sinir Cerrahisi Kliniği, İstanbul The Uncinate Fasciculus (UF) is a significant component of brain white matter, composed of long association fibers that connect the orbitofrontal cortex and the anterior temporal lobe. The UF is believed to be associated with episodic memory, language, and socioemotional functions. Given its central role in regulating episodic memory, language, and behavioral functions, the UF is associated with various disorders. In the literature, UF damage has been indicated to lead to psychiatric disorders, dementia, language, and behavioral disturbances. However, UF"s functions still need to be fully comprehended. This review aims to provide an overview of the structure and functions of the UF by utilizing techniques including white matter dissections, Diffusion Tensor Imaging (DTI) modalities, and analysis of literature data. Anahtar Kelimeler : Uncinate fasciculus, White matter, Anatomical dissection, Function, Diffusion tensor imaging, Disorders