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Dokuz Eylül Üniversitesi Tıp Fakültesi Nöroşirürji Anabilim Dalı, İzmir Three patients with multifocal glioma are presented. In spite of new developments imaging techniques, the distinction between multifocal glioma and metastases should require operation. Pathogenesis and pitfalls in the diagnosis of multifocal gliomas are briefly discussed. Anahtar Kelimeler : Astrocytoma, Brain Tumor, Multifocal Glioma