Türk Nöroşirürji Dergisi 1993 , Vol 3 , Num 2
Aydın SAV1, Özlem KAYABEYOĞLU1, Kağan AKKAYAN4, Gülsün EKİCİOĞLU1, Muhittin GÖKMEN3, Neşe APAK3
1Marmara Üniversitesi Tıp Fakültesi patoloji Anabilim Dalı
2Marmara Üniversitesi Tıp Fakültesi Öğrencisi
3İ.T.Ü. Elektrik ve Elektronik Fakültesi Bilgisayar Bilimler Fakültesi
4S.T.F.A. Bilgi İşlem Merkezi, İstanbul
Tissue markers of cellular proliferation have been largely used as a prognostic marker lately. The role of AgNOR (Nucleolar Organizer Region) as a quantitative (numeric) marker has still been debated vigorously in the tumors of central nervous system (CNS).

In this particular study. NOR regions were stained on paraffin embedded and sectioned glass slides by silver impregnation in a group of 18 cases of diffuse astrocytomas.

For the calculation of AgNOR areas a specific formula (AgNORlnudeus) was used as a morphologic criterion.

Technically for the analysis pattern recognition computer assisted system was used.

Preliminary results were evaluated and both availability and reproductbility of this particular method was discussed. Anahtar Kelimeler :