Türk Nöroşirürji Dergisi 2007 , Vol 17 , Num 2
Pineal Region Tumour: A Case Report
A. Özcan BİNATLI1, Erel ULUĞ2, İlker ÖZHAN3, Volkan ZİNCİROĞLU4, Bülent SARIKAYA5, M. Feryat DEMİRHAN6, Nurcan ÖZDAMAR7
1,2,3,4,5,6S.B. İzmir Tepecik Eğitim ve Araştırma Hastanesi Beyin ve Sinir Cerrahisi Kliniği, İzmir
7Ege Üniversitesi Tıp Fakültesi, Hastanesi Nöroşirürji Anabilim Dalı, İzmir
Pineal region tumors are derived from cells located in and around the pineal gland (The principle cell of the pineal gland is the pinocyte). Pineal region tumors cover a large spectrum of benign and malignant tumor structures. Pineal region tumors make up 0.4-1.0% of intracranial tumors in adults and 3.0-8.0% of brain tumors in children. The frequency of pineal cell tumors is equal in both sexes. Generally, obstructive type hydrocephalus accompanies this situation. As a result of this, increased intracranial pressure symptoms appear. Initial management of patients with pineal region tumors should be directed at treating hydrocephalus and establishing a diagnosis. MRI and germ cell markers are diagnostically valuable (Alpha-fetoprotein and beta-hCG). The histological diagnosis should be made for the optimal treatment of pineal region tumors, because of the various tumor subtypes. Therapeutic decision-making is based on tumor histology rather than radiation responsiveness. The surgical intervention is curative for benign tumors and germ cell tumors and is positively correlated with the lifespan. In our case, a 25-year-old male patient with a pineal region tumor was operated. The tumor has been totally resected and radiotherapy has been applied after the operation. The pathology was reported as ependymoma. Anahtar Kelimeler : Ependymoma, Obstructive hydrocephalus, Pineal region tumours