Türk Nöroşirürji Dergisi 2008 , Vol 18 , Num 1
Wilson's Disease and Spinal Canal Stenosis: Surgical Treatment for Thoracic and Lumbar Spinal Canal Stenosis in Wilson's Disease
Nail ÖZDEMİR1, Mustafa MİNOĞLU2, Gönül GÜVENÇ3, Çetin ÇEVİK4, Hamit Güneş FERAN5, Hamdi BEZİRCİOĞLU6
1,2,3,5,6İzmir Atatürk Eğitim ve Araştırma Hastanesi, Nöroşirürji Bölümü, İzmir
4İzmir Atatürk Eğitim ve Araştırma Hastanesi, Gastroenteroloji Bölümü, İzmir
Wilson's disease (progressive hepatolenticular degeneration) is an autosomal recessive inherited disorder in which copper pathologically accumulates primarily within the liver and subsequently in the central nervous system and many other organs and tissues. The presence of liver disease, neurological symptoms, and Kayser-Fleischer corneal rings constitute the clinical triad of the disease. Changes of the skeletal system are rare in Wilson'disease. There are a few of reports concerning degenerative changes of the spine, such as spinal canal stenosis and disc herniation in this disease in the literature. We present the case of a 21-year-old male patient, diagnosed with Wilson's disease 4 years ago, who underwent surgical treatment due to thoracic and lumbar spinal canal stenosis. In this article, we discuss the relation of Wilson's disease with degenerative changes of the spine. This condition should be considered in patients with Wilson's disease who present with back pain, leg pain and numbness. Anahtar Kelimeler : Progressive hepatolenticular degeneration, Spinal canal stenosis, Wilson's disease