Türk Nöroşirürji Dergisi 2012 , Vol 22 , Num 1
Central Neurocytoma
Muhammet Bahadır YILMAZ
Kayseri Eğitim ve Araştırma Hastanesi, Beyin ve Sinir Cerrahisi Kliniği, Kayseri, Türkiye Central neurocytoma (CN) was first deccribed by Hassoun et al. In 1982. Central neurocytomas are 0.1-0.5% of all intracranial tumors. Classically, the tumor affects young adults at the third decade. Generally, they are found in the anterior portion of the lateral ventricle. Extraventricular neurocytomas have been reported in a variety of locations. The typical clinical manifestation is consistent with the signs and symptoms associated with obstructive hydrocephalus. CN is WHO grade 2 tumor with a favorable prognosis and malignant clinical course is rare. It has been reported craniospinal spread and recurrence after total resection despite the benign histopathology and clinical course. Gold standart treatment for this tumor is a total resection whenever possible. Radiotherapy is necessary for patients with incomplete resection and atypical neurocytoma. Gamma knife therapy is a suitable method for the small residues after surgery. Chemotherapy rarely used in patients with recurrent tumor. Anahtar Kelimeler : Central neurocytoma, Surgery, Radiation therapy, Stereotactic radiosurgery, Chemotherapy,MIB-1 LI