Türk Nöroşirürji Dergisi 2001 , Vol 11 , Num 2
OPTIC NERVE REGENERATION
Ağahan ÜNLÜ1, Gülşah BADEMCİ1, Zafer AYDIN1, Bermans İSKANDAR2
1Ankara Üniversitesi Tıp Fakültesi, Nöroşirürji Anabilim Dalı, Ankara
2Wisconsin Üniversitesi Tıp Fakültesi, Nöroşirürji Anabilim Dalı, Ankara
Optic nerve regeneration model has been used for exploring the regenerative capacity of central type neurons. The accessibility and affectability of the neuron body which is situated in eye globe are reasons for selections in regeneration experiments. The environment which influence the regenerative capacity of the neuron is also easily investigated in optic nerve model. The environment has been changed in order to search the effects of different factors. The results collected would promote the future experiments in other parts of Central Nervous System. In 12 rats, axonal injury has been done by cutting the optic nerve and regeneration has been induced by grafting sciatic nerve. Regeneration has been detected in 1.02% of cells. Anahtar Kelimeler : Central Nervous System, Regeneration, Optic nerve