Türk Nöroşirürji Dergisi 2014 , Vol 24 , Num 2
Microelectrode Recording and Stimulation in Movement Disorder Surgery
Medikalpark Bahçelievler Hastanesi, Beyin ve Sinir Cerrahi Bölümü, İstanbul, Türkiye AIM: Intraoperative neuronal microrecordings and stimulation can help in localizing specific targets during stereotactic surgeries. This article details our technique and experience in performing micreolectrode recording and stimulation guided thalamic ventral intermediate nucleus, globus pallidus inernus and subthalamic nucleus lesioning and deep brain stimulation cases in the treatment of medically refractory movement disorders.

MATERIAL and METHODS: Microelectrode recording and stimulation by using platinium-iridium microelectrodes with 2-4 micron tips were utilised on 872 consecutive cases with medically refractory movement disorders, and findings and the advantages, as well as risks with microelectrode recording and stimulation technique were evaluated.

RESULTS: The clinical experience from 7.834 single microelectrode recording trajectories from 872 medically refractory movement disorder cases, which were gathered from 1.212 anatomical sites, consisting of 94 thalamic, 464 pallidal and 654 subthalamic areas was evaluated; the thoughts and findings were discussed.

CONCLUSION: The adoption of microelectrode recording and stimulation, as well as clinical testing during the surgery allows the precise identification of location and borders of functional targets and precise location of kinesthetic cells in these structures. In addition to its significant contribution to the results of the surgery, utilisation of microelectrode recording does not have an increased bleeding risk and extended length of surgery time in experienced hands. Anahtar Kelimeler : Microelectrode recording, Deep brain stimulation, Movement disorders surgery, Parkinson’s disease, Subthalamic nucleus