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¹Selçuk Üniversitesi, Tıp Fakültesi, Patoloji Anabilim Dalı, Konya, Türkiye Craniosynostosis is a birth defect in which one or more of the fibrous joints between the bones of your baby"s skull (cranial sutures) close prematurely (fuse), before your baby"s brain is fully formed. Brain growth continues, giving the head a misshapen appearance. Craniosynostosis usually involves fusion of a single cranial suture, but can involve more than one of the sutures in your baby"s skull (complex craniosynostosis). In rare cases, craniosynostosis is caused by certain genetic syndromes (syndromic craniosynostosis). Treating craniosynostosis involves surgery to correct the shape of the head and allow for normal brain growth. Early diagnosis and treatment allow the baby"s brain adequate space to grow and develop. The pathogenesis of craniosynostosis appears to be multifactorial and is not complately understood. The advances in suture biology, molecular genetics and pathology will further contribute to the treatment and prevention of these anomalies. Anahtar Kelimeler : Craniosynostosis, Pathology, Suture