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¹SB İstanbul Medeniyet Üniversitesi, Göztepe Eğitim ve Araştırma Hastanesi, Nöroşirürji Kliniği, İstanbul, Türkiye Craniosynostosis is the pathologic condition of skull resulting from early closure of one or more sutures. It is typically diagnosed by careful inspection and a simple x-ray of the skull. Once diagnosed, it is important to determine whether the disease is part of a syndrome or not. While there are no significant neurological findings other than skull deformity in single suture synostoses, there is a wide spectrum of findings such as increased intracranial pressure (ICP), hydrocephalus, mental retardation, chiari malformation and epilepsy in multisuture (sendromic) synostoses and secondaries. Common symptoms (such as abnormal facial development, midface hypoplasia, cranial anomalies, upper extremity anomalies) in craniofacial syndromes occur in syndromic cases. There are findings related to additional malformations, genetic disorders and other systems findings that accompany multisuture synostoses and secondary ones. These cases should be evaluated and treated for these pathologies in the preoperative period, as well as for craniosynostosis correction. This will increase the success of the surgeon by reducing the mortality and morbidity. Anahtar Kelimeler : Chiari malformation, Hydrocephalus, Intracranial pressure, Craniosynostosis