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¹Uludağ Üniversitesi, Tıp Fakültesi, Beyin ve Sinir Cerrahisi Anabilim Dalı, Bursa, Türkiye
²İstinye Üniversitesi, Bursa VM Medicalpark Hastanesi, Beyin ve Sinir Cerrahisi Bölümü, Bursa, Türkiye Treatment of resistant pain and cancer pain is still one of the major problems in medicine. Cancer pain is seen in 90% of the patients, especially in the terminal stage of the disease, and worsens the quality of life. Although the use of neurosurgical procedures has decreased with the advance of narcotic analgesics, lesion-forming interventions for the spinal cord and brain in patients with resistant pain remain important. The aim of these interventions is to prevent the transmission of pain by forming a lesion in the pain commissural pathways. Cordotomy, trigeminal tractotomy, dorsal root entry zone surgery, extralemniscal myelotomy and rhizotomy are the most commonly used neurosurgical interventions for intractable pain and cancer pain. In this paper, we reviewed recent developments in destructive pain surgery at the level of the brain stem and spinal cord in the light of the current literature. Anahtar Kelimeler : Intractable pain, Cancer pain, Neurosurgical procedures, Neuroablative procedures