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¹Sağlık Bilimleri Üniversitesi Gaziosmanpaşa Eğitim ve Araştırma Hastanesi, Anestezi ve Reanimasyon Kliniği, İstanbul, Türkiye
²Sağlık Bilimleri Üniversitesi Gaziosmanpaşa Eğitim ve Araştırma Hastanesi, Beyin ve Sinir Cerrahisi Kliniği, İstanbul, Türkiye Traumatic brain injury is the leading cause of death and disability. Most survivors live their life with significant disabilities. The effect of direct damage on the brain and the effects of secondary damage and those of the mechanisms against it of the body determine the prognosis in head traumas. The posttraumatic stress response and excessive water retention lead to hyponatremia. Syndromes that can be seen in head traumas and cause an imbalance include inappropriate ADH release, cerebral salt loss syndrome and diabetes insipidus. ICP monitoring is required. Despite appropriate treatment, high-dose barbiturate coma or hypothermia may be used for with ab ICP above 20 mmHg. Mannitol and hypertonic saline are used to lower the intracranial pressure. It is important to avoid hypovolemia, hyperosmolarity and kidney failure. The benefits of using hypertonic solutions are known but further studies are needed to develop a consensus on the dosage. Anahtar Kelimeler : Electrolyte imbalance, Cranial trauma, Fluid replacement