Türk Nöroşirürji Dergisi
2021 , Vol 31 , Num 1
Craniopharyngioma in the Pediatric Population
1Ankara Üniversitesi Tıp Fakültesi, Nöroşirürji Anabilim Dalı, Ankara, Türkiye
Craniopharyngiomas are rare sellar / suprasellar tumors. Although these tumors, which can be seen in both pediatric and adult
age groups, are considered benign, high morbidity rates in the long term have increased the medicopsychosocial burden of the
disease. Almost all of the pediatric craniopharyngioma cases are of the adamantinomatous type. These tumors are closely adjacent
to structures such as the optic apparatus, pituitary, hypothalamus, Willis polygon, and brain stem. Hypothalamic involvement
significantly increases mortality and morbidity rates in such cases. Although the treatment of craniopharyngioma seems to be
determined basically, it can become quite controversial in complicated cases. The need to maintain the balance between tumor
control and quality of life has formed the basic rule in the treatment of this patient population. The management of craniopharyngioma
patients is a challenging process and should be followed by multidisciplinary teams consisting of neurosurgeons, neurologists,
oncologists, endocrinologists, and ophthalmologists. Recent developments show promise for target-based molecular therapies for
inhibition of specific pathways, but further studies are needed.
Anahtar Kelimeler :
Craniopharyngioma, Pediatric, Sellar, Suprasellar, Surgery