Türk Nöroşirürji Dergisi
2021 , Vol 31 , Num 3
Deep Brain Stimulation in Parkinson's Disease: Neuroradiology and Anatomical Targets
1Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Beyin ve Sinir Cerrahisi Anabilim Dalı, Samsun
Parkinson"s disease, first described by James Parkinson in 1817, is the second most common neurodegenerative disease in
the world. The most common motor symptoms are tremor, rigidity and bradykinesia; and cognitive, behavioral and autonomic
complaints may also be present. Nowadays, deep brain stimulation is applied to the subthalamic nucleus, globus pallidus internus,
ventral intermediate nucleus of the thalamus, and pedunculopontine nucleus for the motor symptoms of Parkinson"s disease. In this
section, the anatomy and radiology of the target points for deep brain stimulation used in the treatment of Parkinson"s disease will
be discussed. The locations of these target points, the structures in the neighborhood, and the connection pathways between each
other can explain how the intended effects and undesirable side effects can occur. Thin-section neuroradiological imaging will also
help to reach the target point in the most reliable way.
Anahtar Kelimeler :
Parkinson"s disease, Deep brain stimulation, Anatomy, Neuroradiology