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¹Bitlis Tatvan Devlet Hastanesi, Beyin ve Sinir Cerrahisi Kliniği, Bitlis, Türkiye The human body is the most developed organism and its self-renewal potential is limited. Regenerative medicine aims to provide full recovery of the tissue and organ damages. Regenerative medicine must be evaluated together with the cell. It is fully connected to stem cell therapies. It also integrates stem cell therapies with gene therapies and tissue engineering. This integration will make it easier to overcome the problems that we encounter in treatment arrangements. All these treatment modalities are still developing and they cannot be used as the main treatment in current medical approaches except for hematopoietic diseases. Within the scope of Neurosurgery, the studies continue especially on brain and spinal cord injury and encouraging results are obtained for the future. Anahtar Kelimeler : Regenerative medicine, Stem cell, Tissue engineering, Gene therapy