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Taksim Hastanesi Nöroşirürji Kliniği Taksim – İstanbul The use of fibrin sealant products in neurosurgery is gradually gaining popularity and finding new application fields. By the time the nonneurotoxic and perfect sealing features of the human fibrin have been recognized, the use of these products has become substantial in neurosurgery and especially in neurotraumatology. In our manuscript, we have presented 6 case reports (two of them being peroperative durallaserations) in whom we used fibrin sealant products in our neurosurgical department at Taksim Hospital and their initial outcomes have been documented respectively. Anahtar Kelimeler : Fibrin sealant, liquor fistula, microsurgical anastomosis, peripheral nerve regeneration