2Sağlık Bilimleri Üniversitesi Gazi Yaşargil Eğitim ve Araştırma Hastanesi, Beyin ve Sinir Cerrahisi Kliniği, Diyarbakır, Türkiye DOI : 10.5137/1019-5157.TND.3420 AIM: The systemic immune inflammation index (SII) is a new parameter defined to measure the body's response to inflammation. In this study, we aimed to determine whether this parameter could be used in the follow-up and treatment of patients with ventriculoperitoneal shunt and central nervous system infection, and whether it could provide an idea about the prognosis.
MATERIAL and METHODS: The study included 49 patients who were followed up for ventriculoperitoneal shunt infection between January 2017 and December 2018. SII was calculated with the formula Platelet x neutrophil/lymphocyte.
RESULTS: Most of the patients were male. The most common presenting complaint was fever. The most common etiology of hydrocephalus was spina bifida. Patients were followed up for at least 3 years. The mean shunt infection rate was 1.83±1.40. Mortality was higher in patients with a higher systemic immune inflammation index. However, the number of previous surgeries, external ventricular drainage, age, and etiology of hydrocephalus were not significantly associated with SII.
CONCLUSION: SII may provide an idea about mortality in shunt infections. However, we recommend studies on larger series supported by CSF culture results.
Anahtar Kelimeler : Ventriculoperitoneal shunt, Central nervous system infections, Systemic immune inflammation index