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Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Nöroşirürji ve Histoloji-Embriyoloji Anabilim Dalları, Samsun In this study, octreotid acetate (OA), a synthetic analog of somatostatin was used for the prevention of vasospasm in the experimental rabbit basilar artery subarachnoid hemorrhage (SAH) model. Basilar artery cross-sectional area was measured by using stereological image analysing method as 323±48 um2 X 103 for the control group, 111±7 um2 X 103 for untreated SAH group, 115±5 um2 X 103 for the placebo+SAH group, and 196±17 um2X 103 for the 150 ugr/day OA+SAH group. Differences between the values of treated and untreated groups were statistically significant. Our results suggest that OA treatment can be effective in the prevention of cerebral vasospasm after SAH. Low side effect profile and practical subcutaneous use are other advantages. The results of other clinical and laboratory researchs are necessary to support this experimental results. Anahtar Kelimeler : Cerebral vasospasm, octreotid acetate, subarachnoid hemorrhage