Türk Nöroşirürji Dergisi 2000 , Vol 10 , Num 3
MOLECULAR GENETIC BASIS OF ASTROCYTOMA PROGRESSION
Figen SÖYLEMEZOĞLU
Hacettepe Üniversitesi,Tıp Fakültesi Patoloji,Anabilim Dalı Doçenti, Ankara The past ten years have witnessed extraordinary progress in our understanding of the molecular genetic basis of astrocytoma progression. Affected oncogenes and tumour suppressor genes have been identified and putative tumour suppressor loci have been mapped. Herein, you will find a summary of the data on molecular pathways in the astrocytoma progression. Anahtar Kelimeler : Astrocytoma, glioblastoma, molecular genetics, progression