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¹Atatürk Üniversitesi Tıp Fakültesi Nöroşirürji Anabilim Dalı
²Mersin SSK Hastanesi Nöroşirürji Kliniği In this study, 60 white male hybrid rabbits were used. One 1x1 cm size of dural defect created on left parietal area via craniectomy was sutured with dehydrated human dura mater (DHD) in the first group and with otogenous fascia lata (OFL) in the second group. At the end of follow up period the macroscopic examination of the grafts in boths groups showed that DHD grafts had been perfectly fused to host dura and seen to cause less cortical adhesion than those of OFL. Microscopically, it was also observed that DHD grafts caused less cortical adhesion than OFL and statistically the rate of the capsule formation produced by DHD grafts appeared similar to OFL. In the lights of these findings, it can be concluded that DHD can be used as an ideal dural graft material in such cases which have a large dural defect and refuse to getting of autogenous grafts for cosmetic problems. Anahtar Kelimeler : Dehidrated human duramater, dural defect, graft, fascia lata