Türk Nöroşirürji Dergisi 2001 , Vol 11 , Num 3
ENDOLYMPHATIC SAC TUMOR IN THE HISTOPATHOLOGICAL DIFFERENTIAL DIAGNOSIS OF CEREBELLOPONTINE ANGLE TUMORS
Sevgen ÖNDER1, Gülnur GÜLER1 Servet İNCİ2, Şevket RUACAN1, Figen SÖYLEMEZOĞLU1
1Hacettepe Üniversitesi Tıp Fakültesi Patoloji Anabilim Dalı, Ankara
2Hacettepe Üniversitesi Tıp Fakültesi Nöroşirürji Anabilim Dalı, Ankara
Herein we report two cases of endolymphatic sac tumor in two male patients aging 51 and 35, initially presenting with a complaint of peripheral facial paralysis. Histologically, the neoplasms showed papillary cystadenomatous pattern with cystic spaces lined by epithelial cells. Immunohistochemical studies demonstrated that the epithelial cells were strongly positive for cytokeratin and epithelial membrane antigen, neuron spesific enolase, vimentin and 5-100. Endolymphatic sac tumor is a locally invasive neuroectodermal tumor of the inner ear that may extend into the cerebellopontine angle leading to neurosurgical intervention. The differential diagnosis of cerebellopontine angle tumors and histological features of endolymphatic sac tumor were discussed. Anahtar Kelimeler : Cerebellopontine angle, endolymphatic sac tumor