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Gazi Üniversitesi, Tıp Fakültesi, Beyin ve Sinir Cerrahisi Anabilim Dalı, Ankara, Türkiye Toxoplasma gondii is an obligate intracellular protozoan. Toxoplasmosis is a common infection worldwide. Human infection usually occurs by eating cyst-contaminated raw or undercooked meat. The infection is usually asymptomatic in immune competent patients. Cerebral toxoplasmosis is associated with high mortality and morbidity in patients with acquired immunocopromised state. Cerebral Toxoplasmosis is the most frequent etiology of cerebral mass and opportunistic infection in patients with AIDS. Cerebral toxoplasmosis typically appears as multiple hypodense nodular lesion predominantly in the basal ganglia and at the corticomedullary junction. We are reporting a case of cerebral toxoplasmosis mimicking thalamic mass in a patient. Anahtar Kelimeler : Cerebral toxoplasmosis, Stereotactic biopsy, Thalamic mass, AIDS