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SSK Okmeydanı Eğitim Hastanesi, Nöroşirürji Kliniği, İstanbul Cerebral glioblastoma multiforme is a frequently seen primary cerebral tumor. Cerebral glioblastoma multiforme can spread by local invasion or cerebrospinal fluid. The spreading of cerebral glioblastoma multiforme into the spinal canal by cerebrospinal fluid and causing clinical symptoms because of this spreading are seen rarely. In this report; we present a case of cerebral glioblastoma multiforme which spreads to the spinal canal by cerebrospinal fluid two years after the operation and this is evaluated under the light of literature. Anahtar Kelimeler : Glioblastoma multiforme, metastase, spinal seeding