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Hacettepe Üniversitesi Tıp Fakültesi Nöroşirürji Anabilim Dalı Öğretim Üyesi The question of "Brain Death" has been widely discussed publicly and medically over the last thirty years. Demonstration of absolute loss of entire brain functions in an irreversibly Comatose patients is extremely important. Advances in the neuradiagnostic procedures, in accordance with the progress of general medical science, have provided more precise and reliable information for determination of "Brain Death" in recent years. Anahtar Kelimeler : Irreversible Coma. Brain Death. Brain stem auditory evoked potentials Radionuclide angiography and cerebral perfusion studies