Türk Nöroşirürji Dergisi 2019 , Vol 29 , Num 1
Factors that Increase the Risk of Bleeding in AVM and AVM and Aneurysm Coexistence and Risk Increase
Özhan Merzuk UÇKUN1
1Sağlık Bilimleri Üniversitesi Ankara Numune Hastanesi, Beyin ve Sinir Cerrahisi Kliniği, Ankara, Türkiye Arteriovenous malformations (AVMs), dysplastic dilated arteries and veins are composed of capillary beds, occasional neural parenchyma-free and abnormal vessels in which the arterial blood is discharged into the draining veins. The most common clinical condition of an AVM is intracerebral hemorrhage. A polymorphism in the inflammatory cytokine IL6 was associated with an ICH risk of brain AVM. The natural course of AVMs involves a 2-4% annual bleeding risk. Cerebellar and pial brainstem AVMs have a higher risk of bleeding than supratentorial AVMs. The prevalence of the relationship between AVMs and aneurysm varies between 2.7 and 22.7%. In patients with AVM and aneurysm, the risk of bleeding was 7% in 1 year and 3% in those with AVM. There was a higher risk of bleeding in small-scale AVMs. AVMs with a single drainage vessel were found to be at higher risk of bleeding in some studies. All AVMs should be based on a balance between the risk of treatment that directly affects the patient"s age and general health, and the risk of future bleeding or progressive disability when planning treatment, whether bleeding or not. Anahtar Kelimeler : Aneurysm, Arteriovenous malformation, Bleeding