Türk Nöroşirürji Dergisi 2019 , Vol 29 , Num 3
Surgical Principles in Glioma Surgery
Mehmet Ozan DURMAZ1,Murat GEYIK2
1Sağlık Bilimleri Üniversitesi, Gülhane Eğitim ve Araştırma Hastanesi, Ankara, Türkiye
2Gaziantep Üniversitesi, Tıp Fakültesi, Beyin ve Sinir Cerrahisi Anabilim Dalı, Gaziantep, Türkiye
Surgery is still the mainstay treatment that has a significant affect on overall survival in low grade and high grade glioma treatment. In addition to its pathological diagnostic efficacy, it also improves the quality of life of patients by reducing neurological symptoms and allowing improvement of neurocognitive functions. The primary goal in glioma surgery is to achieve a wide resection rate without increasing the postoperative morbidity of the patient and to benefit the patient"s survival. It is known that gliomas, especially glioblastomas, which are intraaxial tumors, can spread to eloquent brain areas and it is difficult to obtain wide resection rates in this situation. Intraoperative imaging techniques (Neuronavigation, MRI and Ultrasonography), fluorescence assisted neurochemical tumor staining techniques, detection of white matter tracts by MRI assisted diffusion tensor imaging tractography and determination of tumor relationship, cortical or subcortical mapping and neurophysiological monitoring are the assistive techniques used for surgical resection. These techniques reduce perioperative morbidity, and they help to determine the appropriate surgical technique for the patient. In the light of all these surgical technological developments, surgical treatment of gliomas is currently more effective; residual tumor volumes have been significantly reduced and better clinical outcomes have been achieved in these patients. Anahtar Kelimeler : Glioma, Surgery, Prognosis