Türk Nöroşirürji Dergisi 2007 , Vol 17 , Num 3
Germinoma: A Case Report
Ali Özcan BİNATLI1, Erel ULUĞ2, İlker ÖZHAN3, Deniz ALTINEL4, Ümit BAYOL5, Nurcan ÖZDAMAR6
1,2,3 Sağlık Bakanlığı, Nöroşirürji, İzmir
4,5Sağlık Bakanlığı, Patoloji, İzmir
6Ege Üniversitesi Tıp Fakültesi, Nöroşirürji, İzmir
Intracranial germ cell tumors are a heterogeneous group of lesions which occur in children and adults. Intracranial germ cell tumors vary in their geographic incidence; in Western series, they constitute anywhere between 0.4% and 3.4% of patients with primary central nervous system (CNS) tumors, while in series reviewing patients in Japan and the Far East, the incidence of germ cell tumors is five- to eightfold greater. İntracranial germ cell tumors most frequently arise in the pineal and suprasellar region. Germ cell tumors are divided into germinomas and nongerminomatous germ cell tumors. The germinoma is the most common type of intracranial germ cell tumors. CNS germinomas are histologically identical to gonadal seminomas and dysgerminomas. The prognosis of germinomas is generally very good. Germinomas are extremely radiosensitive, and radiation therapy is the standard treatment for intracranial germinoma as over 90% of patients can be effectively treated with radiation therapy. In our case, 32-year-old-female-patient with Germinoma was operated. The tumor has been totally resected and radiotherapy has been applied after the operation. The pathology was reported as germinoma. Anahtar Kelimeler : Germinoma, Intracranial germ cell tumors, Radiotherapy