Türk Nöroşirürji Dergisi 2008 , Vol 18 , Num 2
Use of Antibiotic-Impregnated Shunt Catheters in Children: Clinical Experience
Ümit ÇELİK1, Emine KOCABAŞ2, Emre ALHAN3, Derviş Mansuri YILMAZ4, Tahsin ERMAN5, Şehnaz AYDEMİR6
1,2,3 Çukurova Üniversitesi Tıp Fakültesi, Çocuk Enfeksiyon Bilim Dalı, Adana, Türkiye
4,5 Çukurova Üniversitesi Tıp Fakültesi, Beyin Cerrahi Anabilim Dalı, Adana, Türkiye
6 Çukurova Üniversitesi Tıp Fakültesi, Pediatri Anabilim Dalı, Adana, Türkiye
AIM: Infection is major complication of cerebrospinal shunting procedures. Recently, rifampin-clindamycin-impregnated silicone catheters (AIS) have been developed in an attempt to prevent infections. In this study, we compared the infection rate between antibiotic impregnated and classical shunt system at least six months after implantation of the shunt system.

MATERIAL and METHODS: This study was conducted at the Department of Pediatric Infectious Disease of Cukurova University Hospital between 2005-2007. 12 children (3-138 months) underwent implantation of antibiotic-impregnated catheter (Group 1) and 14 children (3-97 months) were implanted a nonantibiotic shunt system (Group 2). Clindamisin-rifampicin silicone catheter was used in all children who were in group. The Chi-square test was used to compare categorical data.

RESULTS: In one patient in group 1, a new shunt pump system was placed after one month because of pump insufficiency, to make thirteen shunt procedures. Four shunt infections (28.5%) were recorded in group 2 and none in group 1. There was a statistically significant difference between the two groups for shunt infection (p=0.04).

CONCLUSION: Clindamycin-rifampin impregnated silicone catheters prevented shunt infections and there was a statistically significant difference between AIS and the traditional system. Longer follow-up and a larger number of patients are needed to more accurately assess the efficacy of these catheters. Anahtar Kelimeler : Antibiotic impregnated shunt, Child, Shunt infection