Türk Nöroşirürji Dergisi 2011 , Vol 21 , Num 1
Intracranial Tuberculosis Mimicking High Grade Glial Tumor: A Case Report
Ersoy KOCABIÇAK1, Keramettin AYDIN1, Cengiz ÇOKLUK1, Mustafa ARAS2, Ömer ALICI3
1Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Beyin ve Sinir Cerrahisi Anabilim Dalı, Samsun, Türkiye
2Mustafa Kemal Üniversitesi, Tıp Fakültesi, Beyin ve Sinir Cerrahisi Anabilim Dalı, Hatay, Türkiye
3Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Patoloji Anabilim Dalı, Samsun, Türkiye
Central Nervous System tuberculosis most frequently presents as the meningitis followed by intracranial tuberculomas and tbc abcess. İntracranial tuberculomas are usually solitary, 2-6 cm wide ovoid or round shaped caseified or noncaseified lesions according to their contrast enhancement on MRI. The most frequent agent is myc tbc and it may not always be isolated from the CSF or excised material. 74 year old male patient presented with headache and seizures. On brain MRI, there was a 2x2x1.5 cm lesion in the left parietal region which is hypointense on T1WI, hyperintense on T2WI surrounded by a wide edema area and enhancing significantly. Mass lesion was excised. Histopathological examination result was granulomatous reaction compatible with tuberculoma. A quad anti-tbc treatment regime was started. Because of the increasing incidence in developing countries,especially tuberculomas are the pathologies that should be suspected in differential diagnosis of the mass occupying lesions. Mass biopsy protects the patient from the harmful effects of radiotherapy or similar treatments by preventing lesion misdefinition like metastasis or high grade glial tumors . Because of the similarities of neuroimaging methods and clinical course,in cases with suspected high grade glial tumor or solitary metastasis,intracranial tuberculoma should be kept in mind in differential diagnosis. Anahtar Kelimeler : Intracranial tuberculoma, High grade glial tumor, tuberculosis