Türk Nöroşirürji Dergisi 2013 , Vol 23 , Num 1
Giant Cell Glioblastoma Multiforme: Rapid Conus Medullaris Metastasis
Ahmet Fatih ATİK1, Aşkın ŞEKER2, Türker KILIÇ2
1Marmara Üniversitesi, Tıp Fakültesi, Nöroşirürji Anabilim Dalı, İstanbul, Türkiye
2Marmara Üniversitesi, Nörolojik Bilimler Enstitüsü, İstanbul, Türkiye
Glioblastoma Multiforme is very aggresive and rapidly progressing tumor which presents extracranial dissemination rarely. Glioblastome is the most common seen brain tumor among all intracranial tumors. Despite modern surgical and adjuvant treatment metthods, median survival is no longer then 14 months. Factors determining patient survival depend on either hystological subtypes and immunohystochemical markers as well. Eventhough giant cell variant of glioblastoma suggests less invasive nature then the others and spinal metastasis of glioblastome usually occurs in late times of disease, here we present very fast occurence of conus medullaris metastasis, eight weeks after initial diagnosis while patient was having post operative adjuvant treatment. Anahtar Kelimeler : Glioblastoma multiforme, Spinal metastasis, Giant cell variant, ki-67