Türk Nöroşirürji Dergisi 2013 , Vol 23 , Num 2
Akdeniz Üniversitesi, Tıp Fakültesi, Beyin ve Sinir Cerrahisi Anabilim Dalı, Antalya, Türkiye Craniopharyngiomas are epithelial tumors that arise along the craniopharyngeal duct, and account for 5,6 to 13 % of intracranial tumors in children. The first reported description of a craniopharyngioma was by the German pathologist, Friedrich Albert von Zenker in 1857. These lesions remain among the most challenging pathologies for pediatric neurosurgeons because their location and degree of invasion into surrounding neural and vascular structures, namely the hypothalamus, pituitary gland, optic apparatus and circle of Willus, make gross total resection difficult, leading to a high rate of recurrence. Even after complete resection, these lesions have a propensity to recur, but the rate of recurrence increases dramatically when resection is subtotal. Although gross total resection remains the therapeutic mainstay for selected patients, a growing body of literature suggests that conservative surgical strategies, followed by adjuvant fractionated or targeted radiotherapy, may achieve similar levels of tumor control while minimizing visual, neurologic and endocrine complications. Anahtar Kelimeler : Child, Craniopharyngioma, Treatment