Türk Nöroşirürji Dergisi 2014 , Vol 24 , Num - Ek
Intracranial Ependymomas
Nuri Eralp ÇETİNALP, Kerem Mazhar ÖZSOY, Tahsin ERMAN
Çukurova Üniversitesi, Tıp Fakültesi, Beyin ve Sinir Cerrahisi Anabilim Dalı, Adana, Türkiye Intracranial ependymomas are the third most common brain tumors in children while they are relatively rare in adults constituting %2-6 of all intracranial neoplasms. Clinical findings depend on the size, location, and histological grade of the tumor. Supratentorial ependymomas occur more frequently in adults, whereas infratentorial tumors are more common in the pediatric population. Surgical excision is the optimal therapeutic management with a goal of gross total resection because the extent of the resection seems to be the most significant prognostic factor in outcome. Postoperative radiotherapy is recommended, particularly in the care of patients with high-grade ependymomas, whereas its role in the management of low-grade tumors remain controversial. Adjuvant chemotherapy has no definite role in the management of these patients and is not part of standard care. The prognosis in adults is more favorable than in children. Anahtar Kelimeler : Intraventricular tumors, Neuroglial tumors, Ependymoma