Türk Nöroşirürji Dergisi
2014 , Vol 24 , Num 3
Craniopharyngioma and Endoscopic Endonasal Treatment
Ankara Numune Eğitim ve Araştırma Hastanesi, Nöroşirürji Kliniği, Ankara, Turkey
Craniopharyngiomas are benign and rare tumors that develop from squamous epithelium in Rathke’s cleft remnants and are usually located
in the sellar/suprasellar region. There are two pathological subtypes as adamantinomatous and solid papillary. They usually cause endocrine
dysfunction and visual disorders because of their location. Their proximity to important neurovascular structures and the high recurrence
rate continue to pose challenges regarding craniopharyngioma treatment in neurosurgery practice. Endoscopic endonasal surgery (EES) is
able to ensure tumor access and a wide infrachiasmatic field with an effective combination of caudocranial and midline approaches and
without requiring the manipulation of any vital neurovascular structure, when compared with well-defined transcranial approaches (pterional,
subfrontal, presigmoid). Combining this anatomic advantage with high-resolution imaging enables high resection rates, preservation of
endocrine function and visual recovery with EES. EES has therefore become an effective and safe treatment option for both pediatric and adult
craniopharyngiomas.
Anahtar Kelimeler :
Craniopharyngioma, Endoscopic endonasal surgery, Suprasellar