Türk Nöroşirürji Dergisi
2019 , Vol 29 , Num 3
Adjunct Techniques for Surgery of Gliomas
1Ege Üniversitesi, Tıp Fakültesi, Beyin ve Sinir Cerrahisi Anabilim Dalı, İzmir, Türkiye
Glioblastoma is the most common and malignant tumour among all glial tumours. Even though overall glioma incidence is much
higher, the incidence of glioblastoma has been reported as 5.26/100,000. The prognosis of glioblastoma is poor and significantly
reduces the quality of life and survival. Current treatment protocols aim to prolong the life span. Whether benign or malignant, the
life span is directly proportional to the extent of the glial tumour resection. Unlike meningiomas, these tumours cannot be delineated
clearly from the brain parenchyma. New additional techniques including intraoperative magnetic resonance imaging, intraoperative
ultrasound, awake craniotomy, intraoperative brain mapping and the use of fluorescent agents have been developed to ensure
maximum resection with minimal morbidity. All adjunct intraoperative techniques developed for glial tumour surgery aim to reduce
morbidity and increase the extent of resection. Each technique has advantages and disadvantages in terms of cost, difficulty or
ease of usage, and sensitivity. In this review, we aimed to cover all aspects of current adjunct techniques.
Anahtar Kelimeler :
Glioma surgery, Intraoperative MRI, Intraoperative USG, Fluorescent agents, Brain mapping, Awake craniotomy