Türk Nöroşirürji Dergisi 2003 , Vol 13 , Num 1
Kamil Melih AKAY1, Yusuf İZCİ1, Salih DEVECİ2, Ayhan ÖZCAN2, Engin GÖNÜL1, Endener TİMURKAYNAK1, Ömer GÜNHAN2
1Beyin ve Sinir Cerrahisi Anabilim Dalı, Gülhane Askeri Tıp Akademisi Ankara
2Patoloji Anabilim Dalı, Gülhane Askeri Tıp Akademisi Ankara
Objective: To review clinical, radiological and treatment characteristics of primary intracranial lymphomas that are relatively rare tumors in neurosurgery practice and to discuss the results of our treatments.

Methods: Medical records of 4 primary intracranial lymphoma cases were reviewed retrospectively. There were 3 female and one male patients. 3 of the lesions were supratentorial and one was infratentorial.

Results: Headache and nausea/vomiting were the most common presentation sign and symptoms (75 %). We were not able to find any reason for immunosuppression in the cases. All the patients showed clinical remission to corticosteroid treatment. All the patients underwent open surgery. All the lesions were originated from Blymphocytes. Irradiation and chemotherapy were administered to two of the patients. Postoperative survival times were one month in two patients, 12 months in one, and 24 months in one.

Conclusion: Although it has been though that they are common in immunodeficient patients, recently their incidence in the normal population has been increasing. The lesions are mostly originated from B-lymphocytes. As a treatment modality, surgery gives only chance to histopathological examination of the lesion. Although the combination of surgery, radiotherapy and chemotherapy is the most effective treatment modality available, prognosis of primary CNS lymphoma cases is poor. Anahtar Kelimeler : Central nervous system, lymphoma, primary, treatment